The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases
High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...
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Main Authors: | , , , , |
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Format: | Book |
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Elsevier,
2016-05-01T00:00:00Z.
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Call Number: |
A1234.567 |
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Copy 1 | Available |