MAP3K8 is a potential therapeutic target in airway epithelial inflammation

• Váldodahkkit: Chih-Yung Chiu (Dahkki), Saffron A. G. Willis-Owen (Dahkki), Kenny C.C. Wong (Dahkki), Stuart N. Farrow (Dahkki), William O.C. Cookson (Dahkki), Miriam F. Moffatt (Dahkki), Youming Zhang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2024-07-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background We have previously discovered clusters of sequentially negative and positive modulators of acute inflammation during cytokine stimulation in epithelial cells and identified potential targets for therapy within these clusters. MAP3K8 is a druggable kinase that we found to be a hub...