Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Abstract Background Muscle mitochondrial decline is associated with aging‐related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. However, disruptions in proteostasis and autophagy are...

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Main Authors: Christie M. Penniman (Author), Gourav Bhardwaj (Author), Colette J. Nowers (Author), Chandler U. Brown (Author), Taylor L. Junck (Author), Cierra K. Boyer (Author), Jayashree Jena (Author), Jordan D. Fuqua (Author), Vitor A. Lira (Author), Brian T. O'Neill (Author)
Format: Book
Published: Wiley, 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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