Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis

Cholestasis is common in multiple clinical circumstances. The NOD-like receptor protein 3 (NLRP3) inflammasome pathway has been demonstrated to play an important role in liver injury and fibrosis induced by cholestasis. We previously proved that MCC950, a selective NLRP3 inhibitor, alleviates liver...

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Main Authors: Xiaopeng Wang (Author), Guiyang Wang (Author), Junwen Qu (Author), Zhiqing Yuan (Author), Ruogu Pan (Author), Kewei Li (Author)
Format: Book
Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
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3rd Floor Main Library

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