Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice

• Main Authors: Qilin Liu (Author), Yitong Zhao (Author), Haibo Shi (Author), Danwei Xiang (Author), Chunye Wu (Author), Lina Song (Author), Ning Ma (Author), Hongchen Sun (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Extracellular matrix (ECM) protein malfunction or defect may lead to temporomandibular joint osteoarthritis (TMJ OA). Dentin sialophophoprotein (DSPP) is a mandibular condylar cartilage ECM protein, and its deletion impacted cell proliferation and other extracellular matrix alter...