Cytokine Profile of Children Hospitalized with Virologically-Confirmed Dengue during Two Phase III Vaccine Efficacy Trials.

• Main Authors: Anke Harenberg (Author), Aymeric de Montfort (Author), Frédérique Jantet-Blaudez (Author), Matthew Bonaparte (Author), Florence Boudet (Author), Melanie Saville (Author), Nicholas Jackson (Author), Bruno Guy (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Two large-scale efficacy studies with the recombinant yellow fever-17D-dengue virus, live-attenuated, tetravalent dengue vaccine (CYD-TDV) candidate undertaken in Asia (NCT01373281) and Latin America (NCT01374516) demonstrated significant protection against dengue disease during two years...