'Carbon-Monoxide-Releasing Molecule-2 (CORM-2)' Is a Misnomer: Ruthenium Toxicity, Not CO Release, Accounts for Its Antimicrobial Effects

• 主要な著者: Hannah M. Southam (著者), Michael P. Williamson (著者), Jonathan A. Chapman (著者), Rhiannon L. Lyon (著者), Clare R. Trevitt (著者), Peter J. F. Henderson (著者), Robert K. Poole (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological 'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and in animal models, but are reportedly benign towards mammalian cells. CORM-2 (tricarbonyldichlororuthenium(II)...