NRF2 Regulates Cystathionine Gamma-Lyase Expression and Activity in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus

• मुख्य लेखकों: Mohammad Jamaluddin (लेखक), Aline Haas de Mello (लेखक), Nisha Tapryal (लेखक), Tapas K. Hazra (लेखक), Roberto P. Garofalo (लेखक), Antonella Casola (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cystathionine-y-lyase (CSE) is a critical enzyme for hydrogen sulfide (H₂S) biosynthesis and plays a key role in respiratory syncytial virus (RSV) pathogenesis. The transcription factor NRF2 is the master regulator of cytoprotective and antioxidant gene expression, and is degr...