Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance

• Main Authors: Annick V. Hartstra (Author), Pieter F. deGroot (Author), Diogo Mendes Bastos (Author), Evgeni Levin (Author), Mireille J. Serlie (Author), Maarten R. Soeters (Author), Ceyda T. Pekmez (Author), Lars O. Dragsted (Author), Mariette T. Ackermans (Author), Albert K. Groen (Author), Max Nieuwdorp (Author)
• Format: Book
• Published: Wiley, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary Objective Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope‐based hyperinsulinemic euglycemic clamp (HIEC). Metabolomic profiling e...