Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology

Background and purpose: This study aimed at preparation of solid dispersions in order to enhance dissolution of poorly water-soluble atorvastatin using supercritical CO2 technology. Atorvastatin has poor bioavailability of 12%, mainly due to poor water solubility and dissolution. Dispersion of drugs...

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Main Authors: Bashar Altaani (Author), Rana Obaidat (Author), Walaa Malkawi (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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