Nitrooleic Acid Protects against Cisplatin Nephropathy: Role of COX-2/mPGES-1/PGE2 Cascade

• Main Authors: Haiping Wang (Author), Zhanjun Jia (Author), Jing Sun (Author), Liang Xu (Author), Bing Zhao (Author), Kezhou Yu (Author), Meng Yang (Author), Tianxin Yang (Author), Rong Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nitrooleic acid (OA-NO2) is an endogenous lipid product which has novel signaling properties, particularly the activation of peroxisome proliferator-activated receptors. The current study aimed to evaluate the protective effects of OA-NO2 against cisplatin-induced kidney injury in mice. Mice were pr...