Potential Roles of Melatonin in Doxorubicin-Induced Cardiotoxicity: From Cellular Mechanisms to Clinical Application

• Hoofdauteurs: Tanawat Attachaipanich (Auteur), Siriporn C. Chattipakorn (Auteur), Nipon Chattipakorn (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Doxorubicin is a potent chemotherapeutic drug; however, its clinical application has been limited due to its cardiotoxicity. One of the major mechanisms of doxorubicin-induced cardiotoxicity is the induction of oxidative stress. Evidence from in vitro and in vivo studies demonstrates that melatonin...