The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer

• Main Authors: Li Hongzhi (Author), Jiang Yulin (Author), Xin Yijuan (Author), Wei Xiaosong (Author), Jin Tao (Author), Nie Hezhongrong (Author), Fang Hezhi (Author), Shen Lijun (Author), He Jing (Author), Chen Tao (Author), Chen Guorong (Author), Lu Jianxin (Author), Bai Yidong (Author)
• Format: Book
• Published: BMC, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Qualitative and quantitative changes in human mitochondrial DNA (mtDNA) have been implicated in various cancer types. A 4,977 bp deletion in the major arch of the mitochondrial genome is one of the most common mutations associated wi...