Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment

• Main Authors: Mengxin Wang (Author), Stephen Vulcano (Author), Changlu Xu (Author), Renjian Xie (Author), Weijie Peng (Author), Jie Wang (Author), Qiaojun Liu (Author), Lee Jia (Author), Zhi Li (Author), Yumei Li (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced functionality. Mutation or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ribosomopathies in clinic, collectively known...