Process validation and preclinical development of a new PET cerebral blood flow tracer [11C]MMP for initial clinical trials
Abstract Background 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is commonly used for diagnosis of dementia because brain glucose metabolism reflects neuronal activity. However, as [18F]FDG is an analogue of glucose, accumulation of tracer in the brain is affected by plasma glucose levels. In contrast...
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SpringerOpen,
2024-07-01T00:00:00Z.
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