Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel

• Main Authors: Matsuda Tomoyuki (Author), Ito Mie (Author), Ishimaru Sayoko (Author), Tsuruoka Noriko (Author), Saito Tomoaki (Author), Iida-Tanaka Naoko (Author), Hashimoto Norio (Author), Yamashita Toru (Author), Tsuruzoe Nobutomo (Author), Tanaka Hikaru (Author), Shigenobu Koki (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Mechanisms for the atria-specific action potential-prolonging action of NIP-142 ((3R*,4S*)-4-cyclopropylamino-3,4-dihydro-2,2-dimethyl-6-(4-methoxyphenylacetylamino)-7-nitro-2H-1-benzopyran-3-ol), a benzopyran compound that terminates experimental atrial arrhythmia, was examined. In isola...