Increased tumour burden alters skeletal muscle properties in the KPC mouse model of pancreatic cancer

• Main Authors: Ravneet Vohra (Author), Matthew D. Campbell (Author), Joshua Park (Author), Stella Whang (Author), Kayla Gravelle (Author), Yak‐Nam Wang (Author), Joo‐Ha Hwang (Author), David J. Marcinek (Author), Donghoon Lee (Author)
• Format: Book
• Published: Wiley, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia is a multifactorial wasting syndrome that is characterized by the loss of skeletal muscle mass and weakness, which compromises physical function, reduces quality of life, and ultimately can lead to mortality. Experimental models of cancer cachexia have recapitulat...