Induction of whole-body gene deletion via R26-regulated tamoxifen-inducible Cre recombinase activity
Germline deletion of certain genes causes embryonic lethality, therefore, understanding the effect of deletion of such genes on mammalian pathophysiology remains challenging. Tamoxifen (TAM)-inducible Cre recombinase is widely used for tissue-specific and temporal induction of gene deletion in mice....
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Frontiers Media S.A.,
2022-12-01T00:00:00Z.
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A1234.567 |
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