Endothelin receptor B-deficient mice are protected from high-fat diet-induced metabolic syndrome

• Main Authors: Martina Feger (Author), Leonie Meier (Author), Jörg Strotmann (Author), Miriam Hoene (Author), Julia Vogt (Author), Alexandra Wisser (Author), Susanna Hirschle (Author), Marie-Jo Kheim (Author), Berthold Hocher (Author), Cora Weigert (Author), Michael Föller (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Endothelin receptor B (ETB) together with ETA mediates cellular effects of endothelin 1 (ET-1), an autocrine and endocrine peptide produced by the endothelium and other cells. It regulates vascular tone and controls kidney function. Metabolic syndrome is due to high caloric intake and is...