Endothelin receptor B-deficient mice are protected from high-fat diet-induced metabolic syndrome

• Hlavní autoři: Martina Feger (Autor), Leonie Meier (Autor), Jörg Strotmann (Autor), Miriam Hoene (Autor), Julia Vogt (Autor), Alexandra Wisser (Autor), Susanna Hirschle (Autor), Marie-Jo Kheim (Autor), Berthold Hocher (Autor), Cora Weigert (Autor), Michael Föller (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2024-02-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Objective: Endothelin receptor B (ETB) together with ETA mediates cellular effects of endothelin 1 (ET-1), an autocrine and endocrine peptide produced by the endothelium and other cells. It regulates vascular tone and controls kidney function. Metabolic syndrome is due to high caloric intake and is...