Endothelin receptor B-deficient mice are protected from high-fat diet-induced metabolic syndrome

• Egile Nagusiak: Martina Feger (Egilea), Leonie Meier (Egilea), Jörg Strotmann (Egilea), Miriam Hoene (Egilea), Julia Vogt (Egilea), Alexandra Wisser (Egilea), Susanna Hirschle (Egilea), Marie-Jo Kheim (Egilea), Berthold Hocher (Egilea), Cora Weigert (Egilea), Michael Föller (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Endothelin receptor B (ETB) together with ETA mediates cellular effects of endothelin 1 (ET-1), an autocrine and endocrine peptide produced by the endothelium and other cells. It regulates vascular tone and controls kidney function. Metabolic syndrome is due to high caloric intake and is...