Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer

• Prif Awduron: Xiyu Liu (Awdur), Jingjing Li (Awdur), Qingqing Huang (Awdur), Mingming Jin (Awdur), Gang Huang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2024-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Ginsenoside Rh2 (G-Rh2), a steroidal compound extracted from roots of ginseng, has been extensively studied in tumor therapy. However, its specific regulatory mechanism in non-small cell lung cancer (NSCLC) is not well understood. Pyruvate dehydrogenase kinase 4 (PDK4), a central...