Inhibition of SLC40A1 represses osteoblast formation via inducing iron accumulation and activating the PERK/ATF4/CHOP pathway mediated oxidative stress

Objective This study aimed to investigate the effects of solute carrier family 40 member 1 (SLC40A1) on iron accumulation, oxidative stress and differentiation in osteoblasts and potential mechanisms.Methods Mouse preosteoblastic MC3T3-E1 cells were transfected with the SLC40A1 overexpression vector...

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Main Authors: Yu Fang (Author), Wei Li (Author), Chongyang Dong (Author), Binli Gao (Author), Wen Guo (Author), Mingyu Li (Author), Zhichao Jiao (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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