Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS

• Main Authors: Huiyan Shi (Author), Chenzhi Hou (Author), Liqiang Gu (Author), Zhe Wei (Author), Hang Xing (Author), Meiyu Zhang (Author), Shixiao Wang (Author), Longshan Zhao (Author), Kaishun Bi (Author), Xiaohui Chen (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats. A simple and efficient high performance liquid chromatography coupled with mass spectrometry (HPLC-MS) metho...