Gastric mixed large cell neuroendocrine-adenosquamous carcinoma with heterogenous MSH6 loss in Lynch syndrome
Lynch syndrome (LS) is the most common hereditary gastrointestinal cancer predisposition syndrome and is caused by mutations in DNA mismatch repair (MMR) genes. Deficiency of MMR proteins manifests as the microsatellite instability-high (MSI-H) phenotype. Gastric cancer is the second most common non...
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Format: | Book |
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Elsevier,
2021-11-01T00:00:00Z.
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A1234.567 |
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