CD4/CD8 Ratio and KT Ratio Predict Yellow Fever Vaccine Immunogenicity in HIV-Infected Patients.

• Main Authors: Vivian I Avelino-Silva (Author), Karina T Miyaji (Author), Peter W Hunt (Author), Yong Huang (Author), Marisol Simoes (Author), Sheila B Lima (Author), Marcos S Freire (Author), Helio H Caiaffa-Filho (Author), Marisa A Hong (Author), Dayane Alves Costa (Author), Juliana Zanatta C Dias (Author), Natalia B Cerqueira (Author), Anna Shoko Nishiya (Author), Ester Cerdeira Sabino (Author), Ana M Sartori (Author), Esper G Kallas (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:HIV-infected individuals have deficient responses to Yellow Fever vaccine (YFV) and may be at higher risk for adverse events (AE). Chronic immune activation-characterized by low CD4/CD8 ratio or high indoleamine 2,3-dioxygenase-1 (IDO) activity-may influence vaccine response in this popul...