Improved Cell-Penetrating Zinc-Finger Nuclease Proteins for Precision Genome Engineering

• 主要な著者: Jia Liu (著者), Thomas Gaj (著者), Mark C Wallen (著者), Carlos F Barbas, III (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2015-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Safe, efficient, and broadly applicable methods for delivering site-specific nucleases into cells are needed in order for targeted genome editing to reach its full potential for basic research and medicine. We previously reported that zinc-finger nuclease (ZFN) proteins have the innate capacity to c...