Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia

• Main Authors: Fabrizio Pin (Author), Rafael Barreto (Author), Yukiko Kitase (Author), Sumegha Mitra (Author), Carlie E. Erne (Author), Leah J. Novinger (Author), Teresa A. Zimmers (Author), Marion E. Couch (Author), Lynda F. Bonewald (Author), Andrea Bonetto (Author)
• Format: Book
• Published: Wiley, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cachexia frequently occurs in women with advanced ovarian cancer (OC), along with enhanced inflammation. Despite being responsible for one third of all cancer deaths, cachexia is generally under‐studied in OC due to a limited number of pre‐clinical animal models. We aimed to addr...