A Study of Morphological Changes in Renal Afferent Arterioles Induced by Angiotensin II Type 1 Receptor Blockers in Hypertensive Patients

• Main Authors: Yohko Nagai (Author), Fumito Yamabe (Author), Yosuke Sasaki (Author), Takamasa Ishii (Author), Kazushige Nakanishi (Author), Koichi Nakajima (Author), Kazutoshi Shibuya (Author), Tetsuo Mikami (Author), Yoshikiyo Akasaka (Author), Yoshihisa Urita (Author), Nobuaki Yamanaka (Author)
• Format: Book
• Published: Karger Publishers, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Renin-angiotensin-aldosterone system blockers are known to reduce hypertrophy of vascular smooth muscle cells (SMCs) in hypertensive cases. However, we have reported marked proliferative changes of renal afferent arteriolar SMCs in rats induced by a long-term administration of angiotensi...