Missense mutations in Desmocollin-2 N-terminus, associated with arrhythmogenic right ventricular cardiomyopathy, affect intracellular localization of desmocollin-2 in vitro

• Main Authors: Basso Cristina (Author), Occhi Gianluca (Author), Bauce Barbara (Author), Sigalotti Luca (Author), Mancuso Luisa (Author), Zaccolo Manuela (Author), Lorenzon Alessandra (Author), Salamon Michela (Author), Nava Andrea (Author), De Bortoli Marzia (Author), Beffagna Giorgia (Author), Lanfranchi Gerolamo (Author), Towbin Jeffrey A (Author), Thiene Gaetano (Author), Danieli Gian (Author), Rampazzo Alessandra (Author)
• Format: Book
• Published: BMC, 2007-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Mutations in genes encoding desmosomal proteins have been reported to cause arrhythmogenic right ventricular cardiomyopathy (ARVC), an autosomal dominant disease characterised by progressive myocardial atrophy with fibro-fatty replac...