Analysis of Copy Number Variations in Solid Tumors Using a Next Generation Sequencing Custom Panel

• Main Authors: Marta Vives-Usano (Author), Beatriz García Pelaez (Author), Ruth Román Lladó (Author), Mónica Garzón Ibañez (Author), Erika Aldeguer (Author), Sonia Rodriguez (Author), Andrés Aguilar (Author), Francesc Pons (Author), Santiago Viteri (Author), Carlos Cabrera (Author), Maria José Catalán (Author), Irene Moya (Author), María Gonzalez Cao (Author), Juan José García-Mosquera (Author), Alejandro Martinez-Bueno (Author), Ekaterina Meshoulam (Author), Nuria Jordana (Author), Laura Berrocal (Author), Rafael Rosell (Author), Miguel Angel Molina (Author), Clara Mayo de las Casas (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Somatic copy number variations (CNV; i.e., amplifications and deletions) have been implicated in the origin and development of multiple cancers and some of these aberrations are designated targets for therapies. Although FISH is still considered the gold standard for CNV detection, the increasing nu...