DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection

• Main Authors: Ángela del Castillo-Izquierdo (Author), José María Moreno-Navarrete (Author), Jessica Latorre (Author), María Arnoriaga-Rodríguez (Author), Marta Ballanti (Author), Giovanni Monteleone (Author), Omero Alessandro Paoluzi (Author), Geltrude Mingrone (Author), Josep Puig (Author), Rafael Ramos (Author), Josep Garre-Olmo (Author), Mariona Jové (Author), Reinald Pamplona (Author), Manuel Portero-Otín (Author), Joaquim Sol (Author), Philippe Lefebvre (Author), Bart Staels (Author), Massimo Federici (Author), José Manuel Fernández-Real (Author), Jordi Mayneris-Perxachs (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-11-01T00:00:00Z.
• Fag: article
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Dipeptidyl peptidase 9 (DPP9) is a member of the dipeptidyl peptidase IV family. Inhibition of DPP9 has recently been shown to activate the nucleotide-binding domain leucine-rich repeat 1 (NLRP1) inflammasome. NLRP1 is known to bind nucleic acids with high affinity and directly interact with double...