Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics
A main challenge in realizing the full potential of nucleic acid therapeutics is efficient delivery of them into targeted tissues and cells. N-acetylgalactosamine (GalNAc) is a well-defined liver-targeted moiety benefiting from its high affinity with asialoglycoprotein receptor (ASGPR). By conjugati...
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Format: | Book |
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Elsevier,
2017-03-01T00:00:00Z.
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Internet
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A1234.567 |
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