The Role of IL-1β in the Bone Loss during Rheumatic Diseases

• Main Authors: Piero Ruscitti (Author), Paola Cipriani (Author), Francesco Carubbi (Author), Vasiliki Liakouli (Author), Francesca Zazzeroni (Author), Paola Di Benedetto (Author), Onorina Berardicurti (Author), Edoardo Alesse (Author), Roberto Giacomelli (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several inflammatory diseases have been associated with increased bone resorption and fracture rates and different studies supported the relation between inflammatory cytokines and osteoclast activity. The main factor required for osteoclast activation is the stimulation by receptor activator of nuc...