Study protocol: baby-OSCAR trial: Outcome after Selective early treatment for Closure of patent ductus ARteriosus in preterm babies, a multicentre, masked, randomised placebo-controlled parallel group trial

• Main Authors: Samir Gupta (Author), Edmund Juszczak (Author), Pollyanna Hardy (Author), Nimish Subhedar (Author), Jonathan Wyllie (Author), Wilf Kelsall (Author), Sunil Sinha (Author), Sam Johnson (Author), Tracy Roberts (Author), Elisabeth Hutchison (Author), Justine Pepperell (Author), Louise Linsell (Author), Jennifer L. Bell (Author), Kayleigh Stanbury (Author), Marketa Laube (Author), Clare Edwards (Author), David Field (Author), on behalf of the 'The Baby-OSCAR Collaborative Group' (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The question of whether to treat patent ductus arteriosus (PDA) early or wait until symptoms appear remains high on the research agenda for neonatal medicine. Around 7000 extremely preterm babies under 29 weeks' gestation are born in the UK every year. In 40% of cases the PD...