Helminth-associated systemic immune activation and HIV co-receptor expression: response to albendazole/praziquantel treatment.

• Main Authors: Mkunde Chachage (Author), Lilli Podola (Author), Petra Clowes (Author), Anthony Nsojo (Author), Asli Bauer (Author), Onesmo Mgaya (Author), Dickens Kowour (Author), Guenter Froeschl (Author), Leonard Maboko (Author), Michael Hoelscher (Author), Elmar Saathoff (Author), Christof Geldmacher (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: It has been hypothesized that helminth infections increase HIV susceptibility by enhancing systemic immune activation and hence contribute to elevated HIV-1 transmission in sub-Saharan Africa. OBJECTIVE: To study systemic immune activation and HIV-1 co-receptor expression in relation to...