Purinergic signaling: A gatekeeper of blood-brain barrier permeation

• Main Authors: Yuemei Wang (Author), Yuanbing Zhu (Author), Junmeng Wang (Author), Longcong Dong (Author), Shuqing Liu (Author), Sihui Li (Author), Qiaofeng Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This review outlined evidence that purinergic signaling is involved in the modulation of blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is critical for maintaining the homeostasis of the brain microenvironment. BBB integrity is maintained primarily by endo...