Darunavir Nanoformulation Suppresses HIV Pathogenesis in Macrophages and Improves Drug Delivery to the Brain in Mice

Although antiretroviral therapy (ART) can suppress peripheral HIV, patients still suffer from neuroHIV due to insufficient levels of ART drugs in the brain. Hence, this study focuses on developing a poly lactic-co-glycolic acid (PLGA) nanoparticle-based ART drug delivery system for darunavir (DRV) u...

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Main Authors: Lina Zhou (Author), Sandip Godse (Author), Namita Sinha (Author), Sunitha Kodidela (Author), Udai Singh (Author), Santosh Kumar (Author)
Format: Book
Published: MDPI AG, 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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