Expanding the antiprotozoal activity and the mechanism of action of n-butyl and iso-butyl ester of quinoxaline-1,4-di-N-oxide derivatives against Giardia lamblia, Trichomonas vaginalis, and Entamoeba histolytica. An in vitro and in silico approach

• Main Authors: Alonzo González-González (Author), Oscar Sánchez-Sánchez (Author), Lilián Yépez-Mulia (Author), Timoteo Delgado-Maldonado (Author), Lenci K. Vázquez-Jiménez (Author), Gabriel López-Velázquez (Author), José Ignacio de la Mora-de la Mora (Author), Sebastian Pacheco-Gutierrez (Author), Laura Chino-Ríos (Author), Diego Arias (Author), Adriana Moreno-Rodríguez (Author), Alma Paz-González (Author), Eyra Ortíz-Pérez (Author), Gildardo Rivera (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, n-butyl and iso-butyl quinoxaline-7-carboxylate-1,4-di-N-oxide derivatives were evaluated in vitro against Giardia lamblia (G. lamblia), Trichomonas vaginalis (T. vaginalis), and Entamoeba histolytica (E. histolytica). The potential mechanism of action determination was approached by...