A population pharmacokinetic model using allometric scaling for baricitinib in patients with juvenile idiopathic arthritis

• Main Authors: Rodney L. Decker (Author), C. Steven Ernest II (Author), David B. Radtke (Author), Rona Wang (Author), Joana Araújo (Author), Stuart Y. Keller (Author), Xin Zhang (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Baricitinib is approved for the treatment of rheumatoid arthritis (RA) in more than 70 countries, and juvenile idiopathic arthritis (JIA) in the European Union. Population pharmacokinetic (PK) models were developed in a phase 3 trial to characterize PK in pediatric patients with JIA and ide...