A mini review of small-molecule inhibitors targeting palmitoyltransferases

• Main Authors: Xiaotong Hu (Author), Xinyue Zhu (Author), Wei Yu (Author), Yiwen Zhang (Author), Kan Yang (Author), Zhenming Liu (Author), Xiaoqiang Qiao (Author), Yali Song (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Palmitoylation occurs when fatty acids (such as palmitic acid) create covalent bonds between cysteine, serine, threonine, or other residues in proteins. The downstream effect of palmitoylation depends on the protein being palmitoylated because its blockage can render the protein useless in terms of...