Suppression of Intracellular Reactive Oxygen Species in Human Corneal Epithelial Cells via the Combination of Quercetin Nanoparticles and Epigallocatechin Gallate and In Situ Thermosensitive Gel Formulation for Ocular Drug Delivery

• Glavni autori: Chuda Chittasupho (Autor), Taepin Junmahasathien (Autor), Jiratchaya Chalermmongkol (Autor), Raksakul Wongjirasakul (Autor), Phuriwat Leesawat (Autor), Siriporn Okonogi (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Oxidative stress can cause several severe ophthalmological diseases. In this study, we developed a thermosensitive gel as a delivery system for two antioxidant substances, namely, quercetin and epigallocatechin gallate. The quercetin was loaded in the PLGA nanoparticles using a solvent displacement...