Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System

• Main Authors: Shuaishuai Zhang (Author), Junqin Li (Author), Huijie Jiang (Author), Yi Gao (Author), Pengzhen Cheng (Author), Tianqing Cao (Author), Donglin Li (Author), Jimeng Wang (Author), Yue Song (Author), Bin Liu (Author), Hao Wu (Author), Chunmei Wang (Author), Liu Yang (Author), Guoxian Pei (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our previous studies found that sensory nerve tracts implanted in tissue-engineered bone (TEB) could result in better osteogenesis. To explore the mechanism of the sensory nerve promoting osteogenesis in TEB in vitro, a transwell coculture experiment was designed between dorsal root ganglion (DRG) c...