Extra-Nuclear Functions of the Transcription Factor Grainyhead-Like 3 in the Endothelium-Interaction with Endothelial Nitric Oxide Synthase

• Main Authors: Kirsten Jander (Author), Jan Greulich (Author), Stefanie Gonnissen (Author), Niloofar Ale-Agha (Author), Christine Goy (Author), Philipp Jakobs (Author), Sabrina Farrokh (Author), Corina Marziano (Author), Swapnil K. Sonkusare (Author), Judith Haendeler (Author), Joachim Altschmied (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of endothelial nitric oxide synthase (eNOS). We now show that a large portion of the protein is locali...