SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner

• Main Authors: Shouji Zhang (Author), Shulin Zhao (Author), Yanhua Qi (Author), Boyan Li (Author), Huizhi Wang (Author), Ziwen Pan (Author), Hao Xue (Author), Chuandi Jin (Author), Wei Qiu (Author), Zihang Chen (Author), Qindong Guo (Author), Yang Fan (Author), Jianye Xu (Author), Zijie Gao (Author), Shaobo Wang (Author), Xing Guo (Author), Lin Deng (Author), Shilei Ni (Author), Fuzhong Xue (Author), Jian Wang (Author), Rongrong Zhao (Author), Gang Li (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As one of the most common post-transcriptional modifications of mRNAs and noncoding RNAs, N6-methyladenosine (m6A) modification regulates almost every aspect of RNA metabolism. Evidence indicates that dysregulation of m6A modification and associated proteins contributes to glioblastoma (GBM) progres...