Csseverin inhibits apoptosis through mitochondria-mediated pathways triggered by Ca2 + dyshomeostasis in hepatocarcinoma PLC cells.

• Main Authors: Mengchen Shi (Author), Lina Zhou (Author), Lu Zhao (Author), Mei Shang (Author), Tongtong He (Author), Zeli Tang (Author), Hengchang Sun (Author), Pengli Ren (Author), Zhipeng Lin (Author), Tingjin Chen (Author), Jinyun Yu (Author), Jin Xu (Author), Xinbing Yu (Author), Yan Huang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Numerous experimental and epidemiological studies have demonstrated a link between Clonorchis sinensis (C. sinensis) infestation and cholangiocarcinoma (CCA) as well as hepatocellular carcinoma (HCC). The underlying molecular mechanism involved in the malignancy of CCA and HCC has not yet been addre...