Cryptotanshinone Attenuates Airway Remodeling by Inhibiting Crosstalk Between Tumor Necrosis Factor-Like Weak Inducer of Apoptosis and Transforming Growth Factor Beta 1 Signaling Pathways in Asthma

• Main Authors: Chongyang Wang (Author), Mingyu Zheng (Author), Yunho Choi (Author), Jingzhi Jiang (Author), Li Li (Author), Junfeng Li (Author), Chang Xu (Author), Zhemin Xian (Author), Yan Li (Author), Hongmei Piao (Author), Liangchang Li (Author), Guanghai Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study is to investigate the effect of cryptotanshinone (CTS) on airway remodeling and the possible mechanism. Male BALB/c mice were pretreated with CTS or dexamethasone 30 min before nebulized inhalation of ovalbumin (OVA). CTS significantly inhibited OVA-induced increases of eosinophils and neu...