Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis

• Main Authors: Shealy David (Author), Gardner Debra (Author), Wu Bin (Author), Song Zheng (Author), Liang Bailin (Author), Song Xiao-Yu (Author), Wooley Paul H (Author)
• Format: Book
• Published: BMC, 2009-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Interleukin-6 is a multifunctional cytokine that is critical for T/B-cell differentiation and maturation, immunoglobulin secretion, acute-phase protein production, and macrophage/monocyte functions. Extensive research into the biology of IL-6 has implicated IL-6...