Identification of bioactive anti-angiogenic components targeting tumor endothelial cells in Shenmai injection using multidimensional pharmacokinetics

• Main Authors: Chongjin Zhong (Author), Chao Jiang (Author), Suiying Ni (Author), Qizhi Wang (Author), Lingge Cheng (Author), Huan Wang (Author), Qixiang Zhang (Author), Wenyue Liu (Author), Jingwei Zhang (Author), Jiali Liu (Author), Mulan Wang (Author), Min Jin (Author), Peiqiang Shen (Author), Xuequan Yao (Author), Guangji Wang (Author), Fang Zhou (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Shenmai injection (SMI) is a well-defined herbal preparation that is widely and clinically used as an adjuvant therapy for cancer. Previously, we found that SMI synergistically enhanced the activity of chemotherapy on colorectal cancer by promoting the distribution of drugs in xenograft tumors. Howe...