Molecular docking-based virtual screening and computational investigations of biomolecules (curcumin analogs) as potential lead inhibitors for SARS-CoV-2 papain-like protease

• Main Authors: Taufik Muhammad Fakih (Author), Ritmaleni (Author), Rahadian Zainul (Author), Muchtaridi Muchtaridi (Author)
• Formato: Libro
• Publicado: Pensoft Publishers, 2024-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

In the effort to combat SARS-CoV-2 infection, researchers are currently exploring the repurposing of conventional antiviral drugs, despite their limited efficacy. The SARS-CoV-2 virus encodes a papain-like protease (PLpro), which not only plays a crucial role in viral replication but also cleaves ub...